Psychophysiology involves recording physiological responses at the periphery, and using these as a gauge of central changes in cognition, motivation or affect. Psychophysiology can be used to measure short-term, stimulus locked responses, or longer term changes in state. Our laboratories at LJMU are equipped to record a range of psychophysiological responses, including facial electromyography (EMG), the electrocardiogram (ECG), and galvanic skin responses (GSR). Measuring fine levels of activity in specific facial muscles, using EMG, provides an objective, immediate, and non-interruptive tool for inferring the valence of a participant’s response to a stimulus. ECG and GSR can also be used to measure rapid orienting and arousal responses, and frequency analyses of these measures provide insight into more sustained changes in autonomic state.